Table 5.
Univariable and multivariable analysis of risk factors for clinically relevant postoperative pancreatic fistula in high-risk of pancreatic fistula patients
| Univariable analysis | Multivariable analysis | |||||
|---|---|---|---|---|---|---|
| OR | 95%CI | P-value | OR | 95%CI | P-value | |
| Age (years) | 1.000 | 0.969–1.032 | 0.999 | |||
| Female (ref: male) | 0.976 | 0.502–1.896 | 0.942 | |||
| BMI (kg/m2) | 1.167 | 1.040–1.311 | 0.009 | 1.175 | 1.034–1.335 | 0.013 |
| Hypertension | 2.490 | 1.257–4.932 | 0.009 | 1.791 | 0.838–3.829 | 0.133 |
| Diabetes | 2.234 | 0.871–5.728 | 0.094 | |||
| Smoke | 0.718 | 0.366–1.406 | 0.334 | |||
| Drink | 0.663 | 0.312–1.409 | 0.285 | |||
| Weight Loss | 1.262 | 0.847–1.880 | 0.253 | |||
| Preoperative biliary drainage | 1.354 | 0.645–2.843 | 0.423 | |||
| Preoperative total bilirubin (μmol/L) (ref: ≤ 21) | 1.415 | 0.738–2.715 | 0.296 | |||
| Preoperative direct bilirubin (μmol/L) (ref: ≤ 8) | 1.613 | 0.848–3.069 | 0.145 | |||
| Preoperative CA 199 (U/mL) (ref: ≤ 37) | 0.791 | 0.416–1.506 | 0.476 | |||
| Operative time (min) | 0.999 | 0.997–1.002 | 0.463 | |||
| Intraoperative bleeding (mL) | 1.000 | 0.999–1.001 | 0.815 | |||
| Vascular resection | 0.583 | 0.154–2.208 | 0.427 | |||
| Internal stent (ref: external stent) | 2.680 | 1.149–6.247 | 0.022 | 3.376 | 1.318–8.646 | 0.011 |
| Blood transfusion | 2.214 | 1.134–4.319 | 0.020 | 2.777 | 1.310–5.887 | 0.008 |
| Texture Firm (ref: soft) | 0.276 | 0.033–2.295 | 0.233 | |||
| Pancreatic duct diameter (cm) | 0.003 | 0.000–0.319 | 0.014 | 0.003 | 0.000–0.456 | 0.024 |
| Pancreatic adenocarcinoma or pancreatitis (ref: ampullary, duodenal, cystic, islet cell, etc.) | 1.480 | 0.636–3.440 | 0.363 | |||
The italic values reflected that there was a significant difference between the two groups