Table 2.

Association of GRS with detailed features of colonoscopy outcomes

Variables	No. subjects	GRS, mean (95% CI)	OR (95% CI)	p
No polyps or HP	1249	0.97 (0.95–0.99)	1
Adenomatous polyps	520	1.02 (1–1.05)	1.61 (1.24–2.08)	< 0.001
Polyp size < 0.5 cm	203	1.02 (0.97–1.06)	1.49 (1.03–2.13)	0.07
Polyp size ≥ 0.5 cm	316	1.03 (1–1.07)	1.68 (1.23–2.27)	< 0.001
Advanced adenoma	126	1.02 (0.97–1.08)	1.56 (0.99–2.42)	0.10
Total no. of polyps
No. = 1	304	1.04 (1–1.07)	1.77 (1.3–2.41)	< 0.001
No. > 1	216	1.01 (0.96–1.15)	1.38 (0.96–1.96)	0.14
Location
CA	296	1.02 (0.98–1.06)	1.56 (1.14–2.12)	0.02
TD	197	1.02 (0.97–1.06)	1.49 (1.02–2.14)	0.08
RS	159	1.02 (0.97–1.08)	1.57 (1.05–2.33)	0.06

GRS genetic risk score, CI confidence interval, OR odds ratio, HP hyperplastic polyp(s), BMI body mass index, CA cecum/ascending colon, TD transverse/descending colon, RS rectum and sigmoid colon