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. 2021 Feb 13;21:160. doi: 10.1186/s12885-021-07874-w

Table 3.

Associations with overall survival and clinicopathologic characteristics in TCGA patients using Cox regression. b. Multivariate survival model after variable selection

Clinicopathologic variable HR (95% CI) p-value
a
Age (continuous) 1.03 (1.02–1.05) 0.000 ***
BAG1 expression (Low vs. High) 2.11 (1.5–2.97) 0.000 ***
Grade 2.25 (1.83–2.77) 0.000 ***
Stage 1.94 (1.72–2.22) 0.000 ***
Cancer Status (tumor free vs. with tumor) 4.92 (3.52–6.91) 0.000 ***
Tumor size 1.90 (1.61–2.31) 0.000 ***
Lymph nodes (positive vs. negative) 3.41 (1.69–6.90) 0.000 ***
Distant metastasis (positive vs. negative) 4.43 (3.18–6.61) 0.000 ***
Gender (male vs. Female) 0.91 (0.65–1.31) 0.576
hemoglobin result (Low vs. Normal) 0.45 (0.30–0.66) 0.000 ***
history of neoadjuvant treatment (Yes vs. No) 2.37 (1.21–4.66) 0.012 *
Serum calcium (Low vs. High) 1.21 (0.81–1.61) 0.431
b
Tumor size 1.25 (0.72–2.17) 0.417
Lymph nodes (positive vs. negative) 1.71 (0.78–3.73) 0.175
Distant metastasis (positive vs. negative) 1.97 (0.79–4.91) 0.145
Stage 1.25 (0.67–2.32) 0.478
BAG1 expression (Low vs. High) 1.75 (1.05–2.90) 0.029*

*:p < 0.05,**:p < 0.01,***:p < 0.001