Table 1.
Demographic features
| Overall n = 108 |
JO-1 (+) n = 33 |
PL-7 (+) n = 30 |
EJ (+) n = 23 |
PL-12 (+) n = 13 |
OJ (+) n = 9 |
P | |
|---|---|---|---|---|---|---|---|
| Age | 56.8 ± 10.5 | 55.0 ± 11.4 | 58.3 ± 10.6 | 57.0 ± 9.1 | 57.5 ± 12.3 | 56.7 ± 8.5 | 0.794 |
| Female | 72 (66.1) | 26 (78.8) | 18 (60) | 15 (65.2) | 7 (53.8) | 6 (66.7) | 0.217 |
| Mechanic’s hands | 27 (25) | 18 (54.5) | 2 (6.7) | 4 (17.4) | 2 (15.4) | 1 (11.1) | 0.002 |
| Clinical features | |||||||
| Skin involvement (Gottron papules/heliotrope rash) | 38 (35.0) | 19 (57.6) | 5 (16.7) | 9 (39.1) | 2 (15.4) | 3 (33.3) | 0.054 |
| PM/DM | 25 (23.1) | 9 (27.3) | 6 (20) | 5 (21.7) | 3 (23.1) | 2 (22.2) | 0.725 |
| Anti-Ro-52 | 73 (67.6) | 29 (87.9) | 19 (63.3) | 21 (91.3) | 3 (23.1) | 1 (11.1) | < 0.001 |
| ILD pattern (radiological and pathological diagnosis by MDT) | |||||||
| OP | 53 (49.1) | 18 (54.5) | 8 (26.7) | 18 (78.3) | 4 (30.8) | 5 (55.6) | |
| NSIP | 42 (38.9) | 13 (39.4) | 15 (50) | 4 (17.4) | 8 (61.5) | 2 (22.2) | |
| OP + NSIP | 9 (8.3) | 2 (6.1) | 3 (10) | 1 (4.3) | 1 (7.7) | 2 (22.2) | |
| UIP | 4 (3.7) | 0 | 4 (13.3) | 0 | 0 | 0 | |
| Positive Anti-Ro-52 antibody | 73 (67.6) | 29 (87.9) | 19 (63.3) | 21 (91.3) | 3 (23.1) | 1 (11.1) | |
| Baseline FVC (% predicted value) | 67.1 | 71.2 | 68.5 | 63.3 | 70.2 | 64.9 | 0.582 |
| Baseline DLCO (% predicted value) | 68.0 | 65.3 | 59.7 | 62.6 | 57.6 | 63.6 | 0.181 |
| Immunosuppressive agents use | 75 (69.4) | 22 (66.7) | 20 (66.7) | 18 (78.3) | 9 (69.2) | 6 (66.7) | N/A |