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. 2021 Feb 10;9:e10762. doi: 10.7717/peerj.10762

Table 1. CpG site differences from EPIC array and the BSAS methods at the 15 loci of differing levels of significance (not significant, nominally significant, and significant after P-value adjustment).

Illumina EPIC array BSAS Difference between methods
Cg/Gene Position in genome Illumina ID β difference P value FDR Adjusted P value β difference P value FDR Adjusted P value β difference
1 AHRR Chr5, GB cg05575921 −0.233 5.33E−12 3.7E−06 −0.041 0.006 0.245 −0.192
2 cg11977356a Chr19 cg11977356 −0.040 0.474 0.999 −0.004 0.406 0.959 −0.036
3 ITPR1 Chr3, GB cg08987995 −0.001 0.572 0.999 0.005 0.820 0.822 −0.006
4 MAGI Chr7, GB cg21121803 −0.008 0.572 0.999 −0.007 0.809 0.959 −0.0004
5 EHMT2 Chr6, GB cg07829740 0.005 0.037 0.999 −0.015 0.071 0.579 0.020
6 PPM1L Chr3, GB cg26406186 −0.006 0.818 0.999 0.011 0.904 0.963 −0.017
7 cg00571101a Chr12 cg00571101 0.004 0.368 0.999 −0.004 0.813 0.952 0.008
8 cg09078959a Chr5 cg09078959 −0.001 0.893 0.999 −0.005 0.001 0.245 0.004
9 cg01614625a Chr7 cg01614625 −0.009 0.370 0.999 −0.006 0.569 0.952 −0.004
10 DP10 Chr2, GB cg05868547 0.006 0.077 0.999 −0.003 0.713 0.952 0.009
11 cg11293828a Chr12 cg11293828 −0.014 0.665 0.999 0.032 0.735 0.952 −0.045
12 CHD7 Chr5, 5′UTR cg19926587 −0.007 0.960 0.999 −0.006 0.429 0.959 −0.001
13 NIPAL4 Chr5, TSS1500 cg17695979 −0.007 0.714 0.999 −0.003 0.106 0.713 −0.004
14 PRDM5 Chr4, GB cg01118724 −0.004 0.734 0.999 0.005 0.116 0.713 −0.009
15 SLC17A7 Chr19, GB cg02624701 −0.043 0.312 0.999 0.018 0.646 0.952 −0.061

Notes.

a

When a cg number is listed, then there is no known gene associated with that CpG site. GB-Gene Body.