Table 3.

Composition of Various SNEDDS Formulations Suggested by Design Expert^® and Their Responses

Formulation Code	Excipients Ratio			Y1 (nm)	Y2 (%)	Y3 (sec)
	X1 (%)	X2 (%)	X3 (%)
F1	0.05	0.4175	0.5325	17.89	98	16
F2	0.14	0.5	0.36	14.69	99.5	15
F3	0.3	0.24	0.46	130	91	38
F4	0.28	0.40	0.32	104.7	94.5	22
F5	0.3	0.5	0.2	114	97	30
F6	0.13	0.42	0.45	23.56	94.5	18
F7	0.21	0.49	0.30	43.41	96	21
F8	0.23	0.31	0.46	87.2	87	26
F9	0.13	0.42	0.45	24.24	95	18
F10	0.14	0.31	0.55	28.07	90	20
F11	0.3	0.33	0.37	125.2	92	25
F12	0.22	0.39	0.39	63.94	90	20
F13	0.06	0.5	0.44	15.89	99	14
F14	0.25	0.2	0.55	132	86	40

Notes: Independent variable: X₁ as oil percentage (Capmul MCM EP), X₂ as surfactant percentage (Tween 20), and X₃ as a co-surfactant percentage (Transcutol P). Dependent variables: globule size (Y₁), %CDR (Y₂) and self-emulsification time (Y₃).