TABLE 4.
Morphoquantitative analyses of the submucosal total neuronal population of the duodenum, jejunum, and ileum of the Wistar and GK groups
| Duodenum | Jejunum | Ileum | ||||
|---|---|---|---|---|---|---|
| Wistar | GK | Wistar | GK | Wistar | GK | |
| Submucosal neuronal density/mm2 a | 278 ± 10 | 290 ± 14 | 287 ± 13 | 249 ± 14 | 300 ± 12 | 244 ± 4.3** |
| Neuronal body area (μm2) b | 242 (193; 293) | 268*** (203; 312) | 217 (173; 271) | 367**** (289; 470) | 274 (226; 334) | 347**** (286; 427) |
| Submucosal neuronal density per ganglion a | 23 ± 1.1 | 22 ± 1.0 | 18 ± 1.1 | 12 ± 0.7**** | 14 ± 0.6 | 10 ± 0.4**** |
| Submucosal ganglion area (μm2) b | 4865 (3685; 6286) | 5398* (4830; 6572) | 3711 (2785; 5782) | 4151 (3360; 5121) | 4465 (3747; 5190) | 4864* (4168; 5879) |
a
Data are expressed as mean ± SEM and compared using Student's t‐test.
b
Data are expressed as median percentiles (25%; 75%) and compared using Mann–Whitney test.
*
p < 0.05;
**
p < 0.01;
***
p < 0.001;
****
p < 0.0001.