Table IV.
Univariate logistic regression estimates of factors associated with sustained remission in rheumatoid arthritis patients
| Demographic and immune variables | OR | 95% CI | P | Variance explained (Nagelkerke R2) |
|---|---|---|---|---|
| Age (yr) | 0.974 | 0.906-1.048 | 0.485 | 0.016 |
| Gender | ||||
| Reference: Female | - | - | - | 0.001 |
| Male | 0.846 | 0.135-5.317 | 0.859 | |
| Duration of illness (months) | 1.003 | 0.988-1.018 | 0.711 | 0.005 |
| Neutrophil to lymphocyte ratio | ||||
| Reference: >4 | - | - | 0.118 | 0.158 |
| ≤2 | 10.5 | 1.029-107.166 | 0.047 | |
| >2-≤4 | 2.625 | 0.359-19.182 | 0.342 | |
| CD3 (cells/µl) | 1 | 0.998-1.002 | 0.961 | 0 |
| CD4 (cells/µl) | 1 | 0.997-1.002 | 0.617 | 0.008 |
| FOXP3 (cells/µl) | 0.835 | 0.593-1.174 | 0.299 | 0.036 |
| CD19 (cells/µl) | 0.997 | 0.989-1.005 | 0.467 | 0.017 |
| CD3:CD19 ratio | 1.049 | 0.9-1.222 | 0.544 | 0.02 |
| FOXP3:CD4 ratio# | 0.059 | - | 0.945 | <0.001 |
| IL-6 (pg/ml) | ||||
| Reference: Above detection limit (>2.2) | - | - | - | |
| Below detection limit (≤2.2) | 0.6 | 0.134-2.681 | 0.504 | 0.015 |
| IL-10 (pg/ml) | ||||
| Reference: Above detection limit (>2) | - | - | - | |
| Below detection limit (≤2) | 2.545 | 0.318-20.38 | 0.379 | 0.025 |
#Point estimate of FOXP3:CD4 has high SE and 95% CI. OR, odds ratio; CI, confidence interval; SE, standard error