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Pathologic Response
| CRLX101 dosing schedule | Dose | N | pCR | Moderate response | Minimal response |
|---|---|---|---|---|---|
| Every other week | 12 mg/m2 | 3 | 1 (33%) | 2 (67%) | 0 |
| 15 mg/m2 | 19* | 3 (16%) | 11 (58%) | 5 (26%) | |
| Weekly | 12 mg/m2 | 3 | 0 | 3 (100%) | 0 |
| 15 mg/m2 | 6 | 2 (33%) | 2 (33%) | 2 (33%) | |
| Total | 30 | 6 (19%) | 17 (55%) | 7 (23%) | |
One patient did not undergo a surgical resection, one had a local excision with moderate response.
