Table 3.
Linear regression results by baseline metabolite. For all models the outcome is percent decrease in BPRS; BPRS and gray matter fraction at baseline are included as covariates in all models.
Parameter Estimates | Model Fit Statistics | ||||||
---|---|---|---|---|---|---|---|
Estimate | SE | p | R2 | F statistic |
F p- value |
||
ACC | NAA | −43.28 | 23.30 | 0.07 | 0.14 | 2.27 | 0.095 |
Glx | −42.76 | 33.53 | 0.21 | 0.11 | 1.61 | 0.201 | |
Cho | −35.03 | 23.77 | 0.15 | 0.12 | 1.81 | 0.161 | |
Hippocampus | NAA | −12.01 | 15.87 | 0.45 | 0.08 | 1.16 | 0.335 |
Glx | 50.17 | 25.21 | 0.05 | 0.15 | 2.37 | 0.084 | |
Cho | −20.06 | 17.27 | 0.25 | 0.10 | 1.44 | 0.245 |
ACC: Anterior cingulate cortex; NAA: N-acetyl-aspartate; Glx: Glutamate+glutamine; Cho: Choline