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. Author manuscript; available in PMC: 2021 Apr 15.
Published in final edited form as: J Neurosci Methods. 2020 Feb 20;336:108631. doi: 10.1016/j.jneumeth.2020.108631

Fig. 6.

Fig. 6.

Symptom improvement with GES differs by disease etiology. Effect of disease etiology on GP symptom score improvement in subjects whose GES parameters are associated with left and right vagal activation compared to those without the same type of vagal response. The top row shows symptom score improvements associated with particular types of vagal response features for all subjects (N = 66 subjects) without considering disease etiology. Rows 2-4 show symptom score improvements for subjects with idiopathic GP (n = 35 subjects), subjects with type 2 diabetic GP (n = 19 subjects), and subjects with type 1 diabetic GP (n = 9 subjects), respectively. In almost every instance, GES-evoked vagal activity was associated with subjects reporting lower symptom score ratings. Note the difference in scale on the y-axes, which highlights the dramatic difference in response to GES among subjects with idiopathic, type 2 diabetic, or type 1 diabetic GP. For type 1 diabetic GP, left vagal Aβ fiber recruitment with GES predicted a significant worsening in the severity of their early satiety symptoms. Data are reported as mean difference in symptom scores ± s.e.m.