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Association of polygenic scores with baseline glycemic traits in SUGAR-MGH
| Polygenic score | Trait | β (95% CI) | P |
|---|---|---|---|
| FG | FG (mmol/L) | 0.13 (0.07, 0.18) | <0.001 |
| FI | Ln FI (pmol/L) | 0.05 (0.003, 0.10) | 0.04 |
| T2D | FG (mmol/L) | 0.05 (−2.1e-5, 0.10) | 0.05 |
| T2D | Ln FI (pmol/L) | 0.009 (−0.04, 0.06) | 0.71 |
Linear regression model was adjusted for age, sex, race/ethnicity, and BMI. β values are reported per SD of polygenic score. P values of <0.05 are in bold and reflect significance. Ln, natural log transformation.
