Table 1.

Leukocytes observed inside the pancreas prior to T-cell accumulation

Leukocytes	Specific for T1D but not T2D	Activated	Localized in the pancreatic islets	Localized in the exocrine pancreas	Elevated in subjects at risk for T1D
Macrophages		X	X
DC	X	X	X
Neutrophils	X	X		X	X
Natural killer cells	X	X	X	X