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. 2021 Jan 14;70(2):347–363. doi: 10.2337/db20-0297

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© 2021 by the American Diabetes Association

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Expression of ECM and matrix adhesion proteins in pancreatic islets. A–C: Heat maps of proteomics data for ECM (panel A), matrix attachment (panel B), and reference (panel C) proteins from isolated human islets (199) (first column) in comparison with transcriptomic data from either isolated human islets (200) (second column) or flow-sorted α-cells (third column) or β-cells (fourth column) (201). Each data set was percentile normalized prior to selection and plotting of the protein subsets. INS, insulin; GCG, glucagon; SST, somatostatin; HK1, hexokinase; SLC2A1, GLUT protein type 1.