Table 1.
Baseline characteristics of patients and main features of CPFA treatment, the results are showed as median and min/max range
| Clinical and biochemical baselines features | |
| Patients (n) | 12 |
| Age (years) | 51 (33–75) |
| M/F (n) | 10/2 |
| Acute liver failure (n) | 3 |
| Acute-on-chronic liver failure (n) | 9 |
| SOFA score | 6 (4–12) |
| CLIF-SOFA (score) | 9 (9–12) |
| MELD (score) | 23 (20–34) |
| HE West Haven Criteria (score) | 1 (1–3) |
| WBC (u/μL) | 11,650 (4930–37,800) |
| Hemoglobin (g/dL) | 9.1 (7.0–13-7) |
| Platelet count (u/μL) | 225,000 (19,000–421,000) |
| CRP (g/dL) | 3.7 (1.29–12) |
| aPtt | 1.64 (0.91–10) |
| INR | 1.34 (1.17–1.97) |
| Sodium (mmol/L) | 138 (132–144) |
| Potassium (mmol/L) | 3.7 (2.8–4.1) |
| Fosfate (mg/dL) | 2.6 (1.1–4.9) |
| Creatinine (mg/dL) | 0.98 (0.55–5.64) |
| Urea (mg/dL) | 50 (193–9) |
| Lactate (mmol/L) | 1.85 (0.9–4.6) |
| Total bilirubin (mg/dL) | 33.25 (21.5–71.21) |
| Indirect bilirubin (mg/dL) | 7.58 (3.58–23.47) |
| Direct bilirubin (mg/dL) | 24.57 (13.99–54.58) |
| Biliary acids (μmol/L) | 185 (84–208) |
| AST (U/L) | 212.5 (66–534) |
| ALT (U/L) | 137 (24–475) |
| AP (U/L) | 166.5 (115–317) |
| GGT( U/L) | 220 (110–428) |
| Albumin (g/dL) | 2.8 (1.9–3.5) |
| Urine output (mL/24 h) | 1500 (300–2000) |
| Liver failure cause | |
| Alcoholic | 8 |
| Viral (HBV–HCV–HDV) | 2 |
| Post-surgical jaundice | 1 |
| Lithiasic cholangitis | 1 |
The min/max range is defined within the brackets
CVC central venous catheter, CLIF-SOFA chronic liver failure-sequential organ failure assessment