Table 4.

Spearman correlation coefficients between change in liver-related biomarkers and changes in weight, waist circumference, Matsuda index and adiponectin at month 24 in the calorie restriction group (n = 143).

	ALT (IU/L)		AST (IU/L)		ALP (IU/L)		GGT (log IU/L)		Bilirubin (mg/dL)
	ρ	p	ρ	p	ρ	p	ρ	p	ρ	p
Weight (kg)	0.30*	<0.01	0.17	0.06	0.17	0.06	0.29*	<0.01	−0.04	0.70
Waist circumference (cm)	0.39*	<0.01	0.30*	<0.01	0.26*	<0.01	0.25*	0.01	−0.11	0.24
Matsuda index	−0.08	0.47	−0.02	0.84	−0.14	0.20	−0.16	0.15	0.14	0.21
Adiponectin (ng/mL)	−0.12	0.20	−0.18	0.05	−0.21*	0.02	−0.25*	0.01	−0.00	0.97

Abbreviations: ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transferase. Values are Spearmans rho (ρ) and P values from simple linear correlations.

^*Significant Spearman correlation (P < 0.05).