Table 3.

Main Effects of Insomnia and Depression Symptoms on Inflammatory Markers

	CRP (ng/mL)			IL-6 (pg/mL)			IL-1β (pg/mL)			TNF-α (pg/mL)
Predictors	Estimates	CI	p	Estimates	CI	p	Estimates	CI	p	Estimates	CI	p
(Intercept)	−0.47	−2.07 – 1.13	0.562	−0.35	−0.57 – −0.13	0.002	−2.07	−2.50 – −1.64	<0.001	−0.28	−0.45 – −0.11	0.002
Insomnia	−0.00	−0.04 – 0.04	0.941	−0.01	−0.01 – 0.00	0.056	0.00	−0.01 – 0.01	0.517	−0.00	−0.00 – 0.00	0.772
Depression	0.02	−0.04 – 0.09	0.461	−0.00	−0.01 – 0.00	0.326	0.00	−0.02 – 0.02	0.847	−0.00	−0.01 – 0.01	0.647
Age	−0.00	−0.02 – 0.01	0.618	0.00	−0.00 – 0.00	0.229	0.01	0.00 – 0.01	0.007	0.00	−0.00 – 0.00	0.231
Gender	−0.76	−1.51 – −0.01	0.047	−0.03	−0.13 – 0.07	0.556	0.06	−0.14 – 0.26	0.531	0.08	0.00 – 0.16	0.041
Ethnicity	−0.40	−1.07 – 0.27	0.241	0.04	−0.06 – 0.13	0.450	−0.04	−0.22 – 0.14	0.682	−0.07	−0.14 – 0.00	0.056
Race	0.49	−0.02 – 0.99	0.058	0.00	−0.07 – 0.07	0.998	0.05	−0.08 – 0.19	0.430	0.03	−0.02 – 0.08	0.252
BMI	0.20	0.16 – 0.23	<0.001	0.02	0.02 – 0.03	<0.001	0.01	−0.00 – 0.02	0.131	0.01	0.01 – 0.01	<0.001
Observations	380			379			378			377
R2 / R2 adjusted	0.267 / 0.253			0.213 / 0.198			0.037 / 0.018			0.097 / 0.079

Note. IL-6 = interluekin-6. CRP = C-reactive protein. TNF-α = tumor-necrosis factor alpha. IL-1β = interleukin-1 beta. BMI = body mass index. Bold values indicate p < .05 associations. CRP was square-root transformed, and IL-6, IL-1β, and TNF-α were all log 10 transformed. Estimates represent unstandardized betas. CI = 95% confidence intervals. Race is coded as 0 = any other race, 1 = white. Ethnicity is coded as 1 = non-Hispanic/Latinx, 2 = Hispanic/Latinx.