Table 2.
Per-vessel plaque features in relation to revascularization in all vessels, and in the subgroup with measured FFR.
| Total Population | Revascularization | No Revascularization | p-value | |
|---|---|---|---|---|
| Total Vessels | 1056 | 271 (26%) | 785 (74%) | |
| Significant Diameter Stenosis > 70% | 135 (12.8%) | 84 (31%) | 51 (6.5%) | <0.0001 |
| Machine-Learning Ischemia Risk Score | 18.7% (6.4-34.8) | 33.6% (21.1-55.0) | 13.0% (4.5-28.1) | <0.0001 |
| Total Plaque Burden | 47.8% (36.1-56.4) | 54.5% (47.2-60.7) | 44.9% (38.0-54.3) | <0.0001 |
| Non-Calcified Plaque Burden | 44.4% (33.1-52.3) | 49.6% (42.7-57.6) | 42.0% (24.8-50.7) | <0.0001 |
| Low-Density Non-Calcified Plaque Burden | 5.6% (2.1-8.8) | 7.9% (5.3-10.7) | 4.3% (0.8-7.9) | <0.0001 |
| Calcified Plaque Burden | 1.5% (0-4.1) | 2.8% (0.7-5.3) | 1.1% (0-3.4) | <0.0001 |
| Contrast Density Difference | 18.5 (5.2-29.8) | 27.1 (18.9-37.0) | 14.1 (0-25.6) | <0.0001 |
| Vessels with FFR | 83 (7.9%) | 41 (49.4%) | 42 (50.6%) | |
| Significant Diameter Stenosis > 70% | 15 (18%) | 9 (10.8%) | 6 (7.2%) | 0.364 |
| Average FFR | 0.80±0.10 | 0.74±0.08 | 0.85±0.07 | <0.0001 |
| Machine-Learning Ischemia Risk Score | 31.4% (18.7-48) | 36.0% (25.5-50.7) | 21.5% (14.9-43.2) | 0.006 |
| Total Plaque Burden | 52.4% (47.0-58.2) | 54.1% (47.6-59.2) | 50.3% (46.2-58.2) | 0.420 |
| Non-Calcified Plaque Burden | 48.2% (41.6-55.2) | 49.2% (41.0-55.4) | 47.2% (43.7-54.8) | 0.800 |
| Low-Density Non-Calcified Plaque Burden | 7.2% (4.3-9.8) | 7.9% (5.8-10.4) | 6.4% (3.6-8.5) | 0.070 |
| Calcified Plaque Burden | 2.4% (0.9-6.1) | 2.9% (1.8-6.2) | 2.1% (0.6-5.7) | 0.140 |
| Contrast Density Difference | 24.0 (16.5-33.7) | 26.2 (21.1-37.7) | 21.6 (10.6-32.4) | 0.016 |
*
Results expressed as mean ± standard deviation, frequency (percent), or median (interquartile range). FFR: Fractional flow reserve.