Table 3.
Per-vessel and Per-patient multivariable analyses for predicting revascularization including clinical risk factors, significant stenosis, and Machine Learning Ischemia Risk Score (per 10% change).
| Per Vessel | Odds Ratio | 95% CI | B | p-value |
|---|---|---|---|---|
| Age (year) | 0.998 | (0.982-1.014) | −0.002 | 0.779 |
| Male Sex | 0.777 | (0.543-1.113) | −0.252 | 0.169 |
| Symptomatic | 0.64 | (0.418-0.979) | −0.447 | 0.039 |
| Hypertension | 0.769 | (0.551-1.073) | −0.263 | 0.122 |
| Hyperlipidemia | 1.063 | (0.771-1.466) | 0.061 | 0.708 |
| Diabetes | 1.074 | (0.755-1.529) | 0.072 | 0.691 |
| Tobacco | 1.058 | (0.694-1.612) | 0.056 | 0.794 |
| Family CAD | 1.486 | (1.069-2.065) | 0.396 | 0.019 |
| Referral Location | 1.212 | (0.842-1.745) | 0.192 | 0.301 |
| Significant Stenosis | 1.981 | (1.201-3.263) | 0.683 | 0.007 |
| ML-IRS (per-10%) | 1.464 | (1.338-1.602) | 0.381 | <0.001 |
| Per Patient | Odds Ratio | 95% CI | B | p-value |
| Age (year) | 1.003 | (0.980-1.027) | 0.003 | 0.815 |
| Male Sex | 1.042 | (0.618-1.760) | 0.042 | 0.876 |
| Symptomatic | 0.523 | (0.262-1.043) | −0.648 | 0.065 |
| Hypertension | 0.666 | (0.405-1.095) | −0.407 | 0.109 |
| Hyperlipidemia | 1.041 | (0.648-1.674) | 0.041 | 0.866 |
| Diabetes | 1.131 | (0.664-1.927) | 0.123 | 0.651 |
| Tobacco | 1.583 | (0.830-3.016) | 0.459 | 0.162 |
| Family CAD | 1.744 | (1.072-2.835) | 0.556 | 0.025 |
| Referral Location | 1.761 | (1.019-3.043) | 0.566 | 0.042 |
| Significant Stenosis | 1.939 | (1.035-3.630) | 0.662 | 0.038 |
| Maximum ML-IRS (per-10%) | 1.211 | (1.192-1.230) | 0.191 | 0.011 |
CAD: Coronary artery disease, ML-IRS: Machine learning ischemia risk score, CI: Confidence Interval