Table 1.
Demographic, Neuroanatomical, and Neuropsychological Characteristics of Patients with Hippocampal Amnesia
| Demographics | Neuroanatomical | Neuropsychological | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient | Sex | Age | Hand. | Ed | Etiology | Damage | HC Volume | WAIS III VIQ | WAIS III Vocab | WAIS III Info | WMS III GMI |
| 1846 | F | 46 | R | 14 | Anoxia | Bilateral HC | −4.23 | 88 | 8 | 8 | 57 |
| 1951 | M | 61 | R | 16 | HSE | Bilateral HC + MTL | −8.10 | 107 | 10 | 11 | 57 |
| 2308 | M | 53 | L | 16 | HSE | Bilateral HC + MTL | N/A | 95 | 11 | 8 | 45 |
| 2363 | M | 53 | R | 18 | Anoxia | Bilateral HC | −2.64 | 112 | 12 | 13 | 73 |
| 2563 | M | 54 | L | 16 | Anoxia | Bilateral HC | N/A | 91 | 9 | 12 | 75 |
| Patient Means | 57.6 | 16 | 98.8 | 10 | 10.4 | 59 | |||||
Key: HC = hippocampus (participants with hippocampal amnesia); F = female. M = male. R = right handed. L = left handed. Ed. = years of education. HSE = Herpes Simplex Encephalitis. + MTL = damage extending into the greater medial temporal lobes. HC Volume = hippocampal volumetric z-scores as measured through high resolution volumetric MRI and compared to a matched healthy comparison group (Allen et al., 2006). WAIS-III VIQ = Wechsler Adult Intelligence Scale–III Verbal Intelligence Quotient, with Vocabulary and Information sub-scores reported. WMS-III GMI = Wechsler Memory Scale–III General Memory Index. Bolded scores are impaired as defined as 2 or more standard deviations below normative data.