Fig. 3.

Replication of TMEV, SFV, and MHV. The diagrams show viral binding and entry, genome replication though minus-strand RNA, discontinuous transcription for MHV, virion/nucleocapsid assembly, and release. For details of translation and protein processing, see Fig. 1. E, small envelope protein; ER, endoplasmic reticulum; ERGIC, endoplasmic reticulum-Golgi intermediate compartment; M, membrane protein; MHV, mouse hepatitis virus; N, nucleocapsid protein; S, spike protein; SFV, Semliki Forest virus; TMEV, Theiler’s murine encephalomyelitis virus; VP0, 1, 3, viral capsid proteins 0, 1, 3