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. 2021 Feb 13;58(6):771–778. doi: 10.1007/s00592-020-01666-7

Table 3.

Multivariable logistic regression model for diagnosis of COVID-19 in South Korea

Variable Multivariable model P-value
OR (95% CI)
Metformin user 0.88 (0.78, 0.99) 0.039
Age, year
20–29 1
30–39 0.79 (0.57, 1.09) 0.158
40–49 0.98 (0.75, 1.27) 0.859
50–59 0.73 (0.58, 0.93) 0.010
60–69 0.60 (0.48, 0.77)  < 0.001
70–79 0.44 (0.34, 0.56)  < 0.001
 ≥ 80 0.36 (0.28, 0.48)  < 0.001
Income level 2020 (Feb)
Q4 (Highest) 1
Q3 0.84 (0.73, 0.97) 0.018
Q2 0.77 (0.68, 0.89)  < 0.001
Q1 (Lowest) 0.80 (0.71, 0.90)  < 0.001
unknown 1.01 (0.69, 1.48) 0.975
Sex, male 1.06 (0.96, 1.17) 0.252
Residence at February, 2020
Seoul 1
Gyeonggi-do 0.95 (0.74, 1.20) 0.647
Daegu 1.05 (0.77, 1.44) 0.743
Gyeongsangbuk-do 1.07 (0.82, 1.39) 0.610
Other area 0.89 (0.67, 1.18) 0.414
Underlying disability 1.05 (0.92, 1.21) 0.486
Charlson comorbidity index, 1 point 1.19 (1.18, 1.20)  < 0.001
Peripheral vascular disease 0.73 (0.63, 0.84)  < 0.001
Renal disease 0.99 (0.79, 1.24) 0.922
Rheumatic disease 0.94 (0.77, 1.14) 0.525
Dementia 2.04 (1.73, 2.40)  < 0.001
Peptic ulcer disease 1.05 (0.93, 1.19) 0.460
Hemiplegia or paraplegia 2.58 (1.87, 3.57)  < 0.001
Moderate or severe liver disease 0.73 (0.37, 1.41) 0.347
Mild liver disease 2.03 (1.84, 2.24)  < 0.001
Chronic pulmonary disease 3.54 (3.20, 3.91)  < 0.001
Cerebrovascular disease 0.98 (0.84, 1.14) 0.777
Congestive heart failure 2.10 (1.83, 2.41)  < 0.001
Myocardial infarction 2.61 (2.10, 3.24)  < 0.001
Malignancy 1.51 (1.37, 1.67)  < 0.001
Metastatic solid tumour 0.91 (0.76, 1.09) 0.302
AIDS/HIV 4.65 (1.17, 18.59) 0.030
Other anti-diabetic drug
Meglitinide 0.78 (0.18, 3.36) 0.737
Dipeptidyl peptidase-4 inhibitors 1.01 (0.87, 1.17) 0.860
Thiazolidinediones 1.06 (0.84, 1.34) 0.619
Sulfonylureas 0.88 (0.75, 1.04) 0.126
Insulin 0.83 (0.63, 1.09) 0.183

AUC of multivariable model: 0.81 (95% CI: 0.80, 0.81)

OR odds ratio; CI confidence interval; AIDS acquired immune deficiency syndrome; HIV human immunodeficiency virus