TABLE 3.
The relationship of miR‐378a‐3p expression with HCC clinicopathological features
| Variables | High miR‐378a‐3p expression (n = 29) | Low miR‐378a‐3p expression (n = 61) | p‐Value |
|---|---|---|---|
| Gender | 0.8436 | ||
| Female | 13 | 26 | |
| Male | 16 | 35 | |
| Age (years) | 0.7965 | ||
| ≤60 | 12 | 27 | |
| >60 | 17 | 34 | |
| HbsAg | 0.7497 | ||
| Negative | 9 | 21 | |
| Positive | 20 | 40 | |
| Cirrhosis | 0.8977 | ||
| Absent | 11 | 24 | |
| Present | 18 | 37 | |
| Serum AFP (ng/mL) | 0.8834 | ||
| ≤20 | 10 | 22 | |
| >20 | 19 | 39 | |
| Tumor size (cm) | 0.0289* | ||
| ≤5 | 16 | 19 | |
| >5 | 13 | 42 | |
| Tumor number | 0.8509 | ||
| Single | 21 | 43 | |
| Multiple | 8 | 19 | |
| Vascular invasion | 0.0410* | ||
| Absent | 15 | 18 | |
| Present | 14 | 43 | |
| TNM stage | 0.0199* | ||
| Early (I/II) | 17 | 20 | |
| Late (III/IV) | 12 | 41 |
*
p < 0.05, Pearson's χ 2 test.
Abbreviations: AFP, alpha‐fetoprotein; TNM, A system for cancer staging. T indicates the size of the tumor and any spread of cancer into nearby tissue; N indicates spread of cancer to nearby lymph nodes; and M indicates metastasis.