Table 1.
Demographic, Memory, Mood, and Anxiety Characteristics of SVHD and Controls
| Variables |
SVHD n = 25 |
Control n = 38 |
p, t/χ 2/U Values | df | 95% Confidence interval |
|---|---|---|---|---|---|
| Mean ± SD/ n (%) | |||||
| Age, median (IQR) | 16.0 (15.0–17.0) | 16.0 (15.0–17.0) | 0.67, 446 | – | 0.66–0.68 |
| Gender Male (%) | 15 (60%) |
19 (50%) |
0.44, 0.61 | 1 | 0.2–1.9 |
|
Ethnicity (%) White Hispanic Other |
13 (52%) 10 (40%) 2 (8%) |
20 (50%) 16 (42%) 2 (8%) |
0.91, 0.20 | 2 | – |
|
Socioeconomic Status, median (IQR) (Annual Household Income) |
$73,167.5 ($54068–$96,758) (n = 24) | $85,696.0 ($74,317.5–$116,633.0) (n = 37) | 0.02, 287 | – | 0.018–0.023 |
| Handedness Right (%) | 23 (92%) | 34 (92%) | 0.74, 0.11 | 1 | 0.13–4.37 |
| BMI (kg/m2), median (IQR) | 21.1 (19.7–3.0) | 21.9 (19.6–24.9) | 0.45, 409.5 | – | 0.44–0.46 |
| Total Brain Tissue Volume (L) | 1.14 ± 0.14 | 1.23 ± 0.11 | 0.005, 2.9 | 61 | 0.03–0.16 |
| MoCA Total, median (IQR) | 23 (20.5–25.0) | 29 (27.8–30.0) | <0.001, 38.5 | – | 0–0.0003 |
| Visuospatial/ EF (MoCA), median (IQR) | 4.0 (3.0–5.0) | 5.0 (5.0–5.0) | <0.001, 187 | – | 0–0.0003 |
| Naming (MoCA), median (IQR) | 3.0 (3.0–3.0) | 3.0 (3.0–3.0) | 0.03, 418 | – | 0.05–0.06 |
| Attention (MoCA), median (IQR) | 4.0 (3.0–5.0) | 6.0 (6.0–6.0) | <0.001, 175 | – | 0–0.0003 |
| Language (MoCA), median (IQR) | 2.0 (1.0–2.0) | 3.0 (2.0–3.0) | <0.001, 196 | – | 0–0.0003 |
| Abstraction (MoCA), median (IQR) | 1.0 (1.0–2.0) | 2.0 (2.0–2.0) | <0.001, 264 | – | 0–0.0003 |
| Delayed Memory Recall (MoCA), median (IQR) | 2.0 (0.5–3.0) | 4.0 (4.0–5.0) | <0.001, 90 | – | 0–0.0003 |
|
Orientation (MoCA), median (IQR) |
6.0 (6.0–6.0) | 6.0 (6.0–6.0) | 0.49, 446.5 | – | 0.54–0.56 |
| WRAML2 (GMI) Total, median (IQR) | 83.0 (79.0–92.5) | 111 (104.8–118) | <0.001, 52 | – | 0–0.0003 |
| Verbal Memory Index (GMI), median (IQR) | 88.0 (82.0–95.5) | 111 (99.3–114) | <0.001, 129.5 | – | 0–0.0003 |
| Visual Memory Index (GMI) | 98.4 ± 12.8 | 107.5 ± 10.2 | 0.003, 3.1 | 61 | 3.2–14.9 |
| Attention/Concentration (GMI) | 83.5 ± 11.4 | 109.6 ± 10.0 | <0.001, 9.6 | 61 | 20.7–31.6 |
| WRAML2 (GRI) Total | 93.6 ± 12.1 | 112.1 ± 10.7 | <0.001, 6.3 | 60 | 12.6–24.3 |
| Working Memory Index (GRI), median (IQR) | 90.0 (79.5–97.5) | 113.5 (102.0–122.0) | <0.001, 70.5 | – | 0–0.0003 |
| Verbal Recognition Index (GRI), median (IQR) | 93.0 (86.5–104.0) | 108.0 (96.0–115.0) | 0.001, 196.5 | – | 0–0.0003 |
| Visual Recognition Index (GRI), median (IQR) | 90.5 (84.3–108.3) | 109 (102.3–115.8) | <0.001, 191 | – | 0–0.0003 |
| Beck Anxiety Inventory (BAI), median (IQR) | 16.0 (8.0–25.5) | 8.0 (3.8–11.0) | 0.001, 251.5 | – | 0.001–0.002 |
| Patient Health Questionnaire 9, median (IQR) (PHQ‐9) | 6.0 (4.0–10.0) | 3.5 (2.0–5.0) | <0.001, 235.5 | – | 0–0.0005 |
Abbreviations: BMI, body mass index; df, degrees of freedom; EF, Executive Function; GMI, General Memory Index; GRI, General Memory Recognition Index; IQR, interquartile range; MoCA, Montreal Cognitive Assessment; WRAML2, Wide Range Assessment of Memory and Learning Version 2.
* p < .05.