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. 2021 Jan;10(1):136–145. doi: 10.21037/tp-20-173

Table 2. Efficacy of spleen aminopeptide on liver damage.

Variables Total Spleen aminopeptide P value
Without With
Liver transaminase level (1 d before treatment)
   ALT (U/L) 201 [142–271] 189 [137–251] 214 [155–323] 0.478
   AST (U/L) 139 [97–215] 123 [89–201] 155 [102–258] 0.067
Liver transaminase level (2 w after treatment)
   ALT (U/L) 123 [80–161] 125 [96–175] 102 [58–146] 0.001
   AST (U/L) 91 [56–112] 96 [64–110] 76 [43–114] 0.151
Liver transaminase level (4 w after treatment)
   ALT (U/L) 65 [42.3–103] 72 [53–123] 54 [37–89] 0.003
   AST (U/L) 46 [31–78] 46 [36–86] 44 [29–68] 0.137
Jaundice index (1 d before treatment)
   TB (ìmol/L) 103.4 (87.6–152.8) 123.0 (89.6–186.4) 102.6 (80.2–140.3) 0.137
   DB (ìmol/L) 96.5 (65.4–122.2) 102.6 (68.2–141.0) 85.9 (65.2–106.8) 0.103
Jaundice index (2 w after treatment)
   TB (ìmol/L) 67.2 (44.8–91.7) 70.9 (46.4–102.2) 60.15 (43.5–78.5) 0.070
   DB (ìmol/L) 48.2 (31.6–67.5) 53.2 (34.2–70.4) 40.8 (26.2–65.4) 0.046
Jaundice index (4 w after treatment)
   TB (ìmol/L) 35.7 (23.8–57.2) 46.1 (26.4–68.7) 32.5 (23.5–45.5) 0.007
   DB (ìmol/L) 28.5 (18.0–39.7) 35.7 (20.8–45.9) 19.2 (12.8–35.7) 0.002

Data are median (IQR). P values comparing with spleen aminopeptide and without spleen aminopeptide are from χ2, Fisher’s exact test, or Mann-Whitney U test.