Table 3. Effects of spleen aminopeptide on cellular immune function.
Variables | Total | Spleen aminopeptide | P value | |
---|---|---|---|---|
Without | With | |||
1 d before treatment | ||||
CD3+ cells (%) | 72.2 (69.8–76.4) | 71.4 (69.5–76.1) | 72.5 (70.4–76.7) | 0.066 |
CD4+ cells (%) | 40.0±6.1 | 40.6±5.8 | 39.2±6.9 | 0.178 |
CD8+ cells (%) | 22.1±4.7 | 22.4±5.2 | 22.0±4.5 | 0.591 |
NK cells (%) | 13.5 (10.4–17.3) | 13.8 (10.4–16.6) | 12.9 (10.5–18.9) | 0.574 |
B cells (%) | 9.8 (7.9–12.3) | 9.9 (8.8–10.6) | 9.1 (6.9–16.1) | 0.544 |
4 w after treatment | ||||
CD3+ cells (%) | 74 (69.8–76.5) | 70.4 (68.3–75.0) | 70.7 (68.4–73.7) | 0.948 |
CD4+ cells (%) | 44.3±7.7 | 42.3±5.8 | 46.2±7.8 | 0.001 |
CD8+ cells (%) | 20.2±4.2 | 19.9±4.7 | 20.8±3.9 | 0.200 |
NK cells (%) | 11.3 (10.0–14.6) | 12.0 (10.3–15.3) | 10.8 (9.8–14.4) | 0.100 |
B cells (%) | 9.7 (8.3–10.4) | 9.7 (8.6–10.4) | 9.4 (7.8–11.6) | 0.152 |
Data are median (IQR) or mean ± SD. P values comparing with spleen aminopeptide and without spleen aminopeptide are from χ2, Fisher’s exact test, or Mann-Whitney U test.