Skip to main content
. 2021 Jan;10(1):194–203. doi: 10.21037/tp-20-248

Table 1. The manifestations of PURA syndrome in the neonatal period.

Clinical presentation In this paper Literature report
Cases Proportion (%)
Gestational age >41 weeks Yes 21/37 57
Hypotonia Yes 64/66 97
Feeding difficulties Yes 59/72 82
Gastroesophageal reflux Suspicious 14/53 26
Breathing problem (apnea/hypoventilation) Yes 41/72 57
Hypersomnia Yes 24/47 51
Startle hyperresponsiveness No 20/52 38
Hypothermia No 11/31 35
Excessive hiccup in utero Yes 6/11 55