Table 1. Study characteristics and demographic features of MIS-C case studies.
Author | Journal | Study design | Publication time [2020] | Country | City | Patients (n, M/F) | Age (years) | Terms in the title | Ref. ID |
---|---|---|---|---|---|---|---|---|---|
Jones VG | Hosp Pediatr | Case report | Apr 7 | USA | California | 1 [0/1] | 0.5 | KD | (3) |
Rivera-Figueroa EI | Indian Pediatr | Case report (letter) | May 9 | USA | Mississippi | 1 [1/0] | 5 | Incomplete KD | (17) |
Balasubramanian S | Indian Pediatr | Case report (letter) | May 10 | India | Chennai | 1 [1/0] | 8 | Hyper-inflammatory syndrome | (30) |
Verdoni L | Lancet | Cohort study (case series) | May 13 | Italy | Bergamo | 10 [7/3] | 7.3 [2.9–16]‡ | Kawasaki-like disease | (4) |
Rauf A | Indian J Pediatr | Case report | May 15 | India | Kerala | 1 [1/0] | 5 | MIS | (20) |
Belhadjer Z | Circulation | Case series | May 17 | France and Switzerland | NR | 35 [18/17] | 10 [2–16]‡ | MIS-C | (25) |
Waltuch T | Am J Emerg Med | Case series | May 20 | USA | New York | 4 [3/1] | 11 [5–13]‡ | Post-infectious cytokine release syndrome | (13) |
Acharyya BC | Indian Pediatr | Case report (letter) | May 22 | India | West Bengal | 1 [1/0] | 0.3 | KD | (19) |
Deza Leon MP | JPIDS | Case report (letter) | May 22 | USA | Michigan | 1 [0/1] | 6 | PMIS | (11) |
Dolinger MT | J Pediatr Gastroenterol Nutr | Case report | May 22 | USA | New York | 1 [1/0] | 14 | MIS-C | (12) |
Riphagen S | Lancet | Case series (correspondence) | May 23 | UK | London | 8 [5/3] | 8 [4–14]‡ | Hyperinflammatory shock | (5) |
Grimaud M | Ann Intensive Care | Case series | May 25 | France | Paris | 20 [10/10] | 10 [2.9–15]‡ | Acute myocarditis and multisystem inflammatory emerging disease | (26) |
Chiotos K | Journal of the Pediatric Infectious Diseases Society | Case series | May 25 | USA | Pennsylvania | 6 [1/5] | 7.5 [5–14]‡ | MIS-C | (15) |
Labé P | J Eur Acad Dermatol Venereol | Case report (letter) | May 26 | France | Argenteuil | 2 [2/0] | 3, 6 | Erythema multiforme and KD | (27) |
Toubiana J | BMJ | Case series | May 26 | France | Paris | 21 [9/12] | 7.9 [3.7–16.6]‡ | KD like MIS-C | (28) |
Cheung EW | JAMA | Case series (letter) | May 27 | USA | New York | 17 [8/9] | 8 [1.8–16]‡ | MIS | (16) |
Whittaker E | JAMA | Case series | May 29 | UK | Multi-center (8 hospitals in England) | 58* [25/33] | 9 [5.7–14]† | PIMS | (23) |
Miller J | Gastroenterology | Case series | May 30 | USA | New York | 44 [20/24] | 7.3 [0.6–20]‡ | MIS-C | (14) |
Greene AG | Am J Emerg Med | Case report | May 31 | USA | New York | 1 [0/1] | 11 | MIS-C | (18) |
Pouletty M | Ann Rheum Dis | Cohort study (case series) | June 2 | France | Paris | 16 [8/8] | 10 [4.7–12.5]† | Kawa-COVID-19 | (24) |
Yozgat YC | Dermatol Ther | Case report (letter) | June 4 | Turkey | Istanbul | 1 [0/1] | 3 | PMIS | (31) |
Ramcharan T | Pediatr Cardiol | Case series | June 5 | UK | Birmingham | 15 [11/4] | 8.8 [6.4–11.2]† | PIMS | (22) |
Chiu JS | Pediatr Cardiol | Case report | June 9 | USA | Boston | 1 [1/0] | 10 | KD features and Myocarditis | (21) |
Blondiaux E | Radiology | Case Series | June 9 | France | Paris | 4 [1/3] | 9 [6–12]§ | MIS-C | (29) |
*, including 8 cases published in Lancet previously; †, median [IQR]; ‡, median [range]; §, mean [range]. PIMS-TS, pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2; PIMS, pediatric inflammatory multisystem syndrome; MIS-C, multisystem inflammatory syndrome in children; MIS, multisystem inflammatory syndrome; KD, Kawasaki disease; PMIS, Pediatrics multisystem inflammatory syndrome.