Table 2. The association of BRAF V600E mutation and other gene mutations (case, %).
| Gene | BRAF V600E | P value | |
|---|---|---|---|
| Mutation (n=55) | Wild-type (n=13) | ||
| RET | <0.001 | ||
| Mutation | 0 (0.0%) | 7 (53.8%) | |
| Wild-type | 55 (100.0%) | 6 (46.2%) | |
| CHEK2 | 0.575 | ||
| Mutation | 5 (9.1%) | 0 (0.0%) | |
| Wild-type | 50 (90.9%) | 13 (100.0%) | |
| ATM | 1.000 | ||
| Mutation | 3 (5.5%) | 0 (0.0%) | |
| Wild-type | 52 (94.5%) | 13 (100.0%) | |
| TSHR | 0.477 | ||
| Mutation | 2 (3.6%) | 1 (7.7%) | |
| Wild-type | 53 (96.4%) | 12 (92.3%) | |
| GNAS | 1.000 | ||
| Mutation | 3 (5.5%) | 0 (0.0%) | |
| Wild-type | 52 (94.5%) | 13 (100.0%) | |
BRAF, B-Raf proto-oncogene, serine/threonine kinase; RET, rearranged during transfection; CHEK2, checkpoint kinase 2; ATM, ATM serine/threonine kinase; TSHR, thyroid-stimulating hormone receptor; GNAS, guanine nucleotide-binding protein, α-stimulating complex locus.