Table 1. The correlation between ypN0 after NAT and clinicopathological characteristics.
| Characteristics | All patients (n=184) | ypN0 (n=105) | % | P |
|---|---|---|---|---|
| Menopausal status | 0.256 | |||
| Menopause | 67 | 35 | 52.2 | |
| No menopause | 117 | 70 | 59.8 | |
| Pathological types | 0.354 | |||
| Ductal | 156 | 87 | 55.8 | |
| Other | 28 | 18 | 64.3 | |
| Ki-67 | 0.004 | |||
| Low expression | 34 | 13 | 38.2 | |
| High expression | 150 | 92 | 61.3 | |
| Molecular subtypes | 0.805 | |||
| HER2+ | 89 | 53 | 59.6 | |
| HR+ | 52 | 28 | 53.8 | |
| HR- | 37 | 25 | 67.6 | |
| TN | 95 | 52 | 54.7 | |
| Clinical tumor staging | 0.009 | |||
| cT1 | 18 | 12 | 66.7 | |
| cT2 | 89 | 56 | 62.9 | |
| cT3 | 34 | 19 | 55.9 | |
| cT4 | 43 | 18 | 41.9 | |
| Clinical lymph node staging | <0.001 | |||
| cN0 | 37 | 35 | 94.6 | |
| cN1 | 82 | 47 | 57.3 | |
| cN2 | 31 | 12 | 38.7 | |
| cN3 | 34 | 11 | 32.4 | |
| Radiologic response of the primary tumor on MRI | 0.020 | |||
| brCR | 72 | 48 | 66.7 | |
| Non-brCR | 48 | 23 | 47.9 | |
| Missing | 64 | 34 | 53.1 | |
| Radiologic response of the lymph nodes | <0.001 | |||
| ycN0 | 95 | 77 | 81.1 | |
| Non-ycN0 | 89 | 28 | 31.5 | |
| Pathologic response of the primary tumor | <0.001 | |||
| bpCR (ypT0/is) | 79 | 65 | 82.2 | |
| Non-bpCR | 105 | 40 | 38.1 | |
NAT, neoadjuvant therapy; ypN0, pathologically node-negative disease after NAT; HR, hormone receptor; brCR, breast radiologic complete response; ycN0, clinically node-negative disease after NAT; bpCR, breast pathologic complete response; N, number; HER2+, human epidermal growth factor receptor 2 positive; TN, triple-negative; MRI, magnetic resonance imaging.