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. 2021 Jan;10(1):10–22. doi: 10.21037/gs-20-486

Table 2. Comparisons between patients with 3 and 4 identified parathyroid glands.

Characteristics 3 identified parathyroid glands (N=212) 4 identified parathyroid glands (N=1,212) P value
Age, years 41.2±12.9 41.4±11.4 0.800
Sex (male) 59 323 0.721
BMI 23.0±3.5 23.1±4.0 0.676
NG 107 602 0.829
HD 71/212 (33.5%) 269/1,212 (22.2%) <0.001*
Hypertension 24 93 0.074
Diabetes 6 39 0.766
Hypothyroidism 4 22 1.000
Hyperthyroidism 7 27 0.345
Tumor size (mm) 14.3±8.2 14.1±9.0 0.769
Multifocality 58 289 0.235
Capsule invasion 95 491 0.241
TNM stage
   Tx/T1/T2/T3/T4 1/101/10/93/7 7/655/82/408/59 0.068
   Nx/N0/N1a/N1b 1/69/85/57 8/504/399/299 0.065
Accidently resection 30/212 (14.2%) 64/1,212 (5.3%) <0.001*
Hypoparathyroidism
   Transient 116/212 (54.7%) 650/1,212 (53.6%) 0.770
   Permanent 3/212 (1.4%) 18/1,212 (1.5%) 1.000
PTH (pg/mL)
   Preoperative 43.74±9.90 45.09±1.09 0.079
   1-day 15.57±10.08 16.02±10.35 0.514
   1-month 29.88±11.43 34.65±13.77 <0.001*
   3-month 32.85±13.59 37.71±14.40 0.008*
   6-month 34.02±12.78 38.25±13.23 0.015*
   12-month 35.91±13.95 38.61±13.41 0.185
   24-month 33.30±12.69 36.00±12.24 0.280
PTH <14 pg/mL
   1-day 115 (54.5%) 647 (54.5%) 0.999
   1-month 12 (6.5%) 45 (4.1%) 0.140
   3-month 3 (4.3%) 16 (3.0%) 0.792
   6-month 2 (3.0%) 13 (2.3%) 1.000
   12-month 2 (3.8%) 7 (1.8%) 0.676
   24-month 1 (3.7%) 5 (3.2%) 1.000
Ca (mg/dL)
   Preoperative 9.36±0.44 9.40±1.28 0.188
   1-month 9.20±0.52 9.24±0.56 0.529
   3-month 8.96±0.60 9.04±0.56 0.072
   6-month 8.96±0.56 9.08±0.56 0.050
   12-month 9.00±0.56 9.16±0.52 0.031*
   24-month 9.04±0.60 9.08±0.56 0.778
Ca <8.5 mg/dL
   1-month 13 (6.8%) 74 (6.6%) 0.936
   3-month 23 (18.0%) 85 (10.6%) 0.016*
   6-month 17 (14.3%) 53 (7.4%) 0.011*
   12-month 12 (12.4%) 33 (6.4%) 0.040*
   24-month 7 (13.2%) 17 (8.1%) 0.375

*, significantly statistical differences. BMI, body mass index; HD, Hashimoto’s disease; NG, nodular goiter; TNM, tumor node metastasis; PTH, parathyroid hormone; Ca, calcium.