Table 3. Comparisons between patients with 3 and 4 parathyroid glands with no accidental resection.
| Characteristics | 3 parathyroid glands (N=182) | 4 parathyroid glands (N=1,148) | P |
|---|---|---|---|
| Age, years | 41.01±12.35 | 41.39±11.41 | 0.677 |
| Sex (male) | 50 | 303 | 0.759 |
| BMI | 23.00±3.55 | 23.16±3.99 | 0.580 |
| NG | 93 | 577 | 0.834 |
| HD | 64/182 (35.2%) | 254/1,148 (22.1%) | <0.001* |
| Hypertension | 21 | 83 | 0.044* |
| Diabetes | 4 | 36 | 0.491 |
| Hypothyroidism | 3 | 21 | 0.865 |
| Hyperthyroidism | 5 | 24 | 0.772 |
| Tumor size (mm) | 13.80±7.60 | 14.09±9.05 | 0.698 |
| Multifocality | 51 | 278 | 0.251 |
| Capsule invasion | 84 | 464 | 0.144 |
| TNM stage | |||
| Tx/T1/T2/T3/T4 | 1/91/7/78/5 | 7/624/75/392/49 | 0.155 |
| Nx/N0/N1a/N1b | 1/62/69/50 | 8/477/387/275 | 0.281 |
| Hypoparathyroidism | |||
| Transient | 96/182 (52.7%) | 602/1,148 (52.4%) | 0.938 |
| Permanent | 3/182 (1.6%) | 17/1,148 (1.5%) | 1.000 |
| PTH (pg/mL) | |||
| Preoperative | 43.29±9.90 | 45.00±9.81 | 0.034* |
| 1-day | 15.57±9.72 | 16.20±10.35 | 0.439 |
| 1-month | 29.43±11.16 | 34.83±13.86 | <0.001* |
| 3-month | 32.76±13.05 | 37.89±14.40 | 0.009* |
| 6-month | 33.66±12.51 | 38.43±13.23 | 0.009* |
| 12-month | 35.64±14.31 | 38.61±13.50 | 0.164 |
| 24-month | 32.49±11.61 | 35.91±12.24 | 0.217 |
| PTH <14 pg/mL | |||
| 1-day | 95 (52.5%) | 599 (53.3%) | 0.831 |
| 1-month | 10 (6.4%) | 43 (4.1%) | 0.199 |
| 3-month | 3 (5.1%) | 15 (2.9%) | 0.614 |
| 6-month | 2 (3.8%) | 12 (2.3%) | 1.000 |
| 12-month | 2 (4.3%) | 7 (1.9%) | 0.592 |
| 24-month | 1 (4.5%) | 5 (3.2%) | 1.000 |
| Ca (mg/dL) | |||
| Preoperative | 9.32±0.44 | 9.40±1.32 | 0.175 |
| 1-month | 9.24±0.52 | 9.28±0.52 | 0.516 |
| 3-month | 8.96±0.60 | 9.08±0.56 | 0.092 |
| 6-month | 2.25±0.14 | 9.08±0.56 | 0.100 |
| 12-month | 2.26±0.13 | 9.12±0.52 | 0.099 |
| 24-month | 9.16±0.48 | 9.08±0.56 | 0.322 |
| Ca <8.5 mg/dL | |||
| 1-month | 10 (6.2%) | 62 (5.9%) | 0.872 |
| 3-month | 18 (16.5%) | 77 (10.1%) | 0.045* |
| 6-month | 12 (11.8%) | 48 (7.0%) | 0.094 |
| 12-month | 9 (10.6%) | 30 (6.1%) | 0.128 |
| 24-month | 4 (9.3%) | 16 (7.8%) | 0.977 |
*, significantly statistical differences. BMI, body mass index; HD, Hashimoto’s disease; NG, nodular goiter; TNM, tumor node metastasis; PTH, parathyroid hormone; Ca, calcium.