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. Author manuscript; available in PMC: 2021 Feb 14.
Published in final edited form as: Invest New Drugs. 2015 Aug 16;33(5):1093–1099. doi: 10.1007/s10637-015-0277-8

Table 3.

Biomarker levels

Baseline
Change (last cycle – first Cycle)
P Value
Mean Median SD Mean Median SD
IGF-1, ng/mL 114.7 96.5 55 −67.3 −55 35 0.0053
IGFBP-1, ng/mL 14.4 4.5 28 16 5.3 28.9 0.2336
IGFBP-3, ng/mL 2835.4 2776 847.1 −903.3 −687.5 780.6 0.0365

SD standard deviation