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. 2021 Feb 10;13:1233–1243. doi: 10.2147/CMAR.S288589

Table 3.

Univariate and Multivariate Analyses of Factors for the Advanced Phase in All Patients

Variables Univariate Analysis OR (95% CI) p value Multivariate Analysis OR (95% CI) p value
Ages 1.063 (1.029~1.098) <0.001 1.081 (1.039~1.125) <0.001
Gender (Female) 0.656 (0.488~0.961) 0.052 0.332 (0.119~0.926) 0.035
WBC counts (×109/L) 0.214 <0.001
RBC counts (×1012/L) 0.594 (0.356~0.992) 0.047
Hemoglobin (g/L) 0.970 (0.952~0.989) 0.002
RDW at diagnosis (%) 1.264 (1.024~1.559) 0.029 1.469 (1.121~1.925) 0.005
Platelet counts(×109/L) 0.997 (0.996~0.999) 0.006 0.997 (0.994~0.999) 0.001
Eosinophil (%; PB) 0.214 <0.001
Basophil (%; PB) <0.001 (0.001~0.003) 0.011
Smoking status
 Never-smoker Reference
 Ever-smoker 0.991(0.522~1.882) 0.978
 Splenomegaly 0.935 (0.762~1.147) 0.553
Cardiovascular system disease 1.648 (1.103~2.463) 0.001

Note: Cardiovascular system diseases: chronic heart failure, coronary atherosclerotic heart disease and hypertension.