Table 3.
Odds Ratio and 95%CI of Albumin Levels with Clinical Outcomes
| 1st Tertile, <37.3 g/L | 2nd Tertile, 37.3g/L−40.2g/L | 3rd Tertile, >40.2g/L | P for Trend | Albumin Levels (Continuous) | P-value | |
|---|---|---|---|---|---|---|
| Poor functional outcome (mRS score of 3–6) | ||||||
| No. of cases (%) | 141 (69.5) | 111 (54.9) | 90 (45.0) | |||
| Crude model | 2.78 (1.85−4.18) | 1.49 (1.01−2.21) | Ref | 0.001 | 0.91 (0.87−0.94) | 0.001 |
| Model 1 | 2.33 (1.52−3.56) | 1.37 (0.90−2.06) | Ref | 0.002 | 0.92 (0.88−0.95) | 0.004 |
| Model 2a | 2.43 (1.18−5.01) | 1.28 (0.65−2.54) | Ref | 0.046 | 0.89 (0.84−0.96) | 0.011 |
| Death (mRS score of 6) | ||||||
| No. of cases (%) | 68 (33.5) | 58 (28.7) | 29 (14.5) | |||
| Crude model | 2.97 (1.82−4.85) | 2.38 (1.44−3.91) | Ref | 0.001 | 0.92 (0.89−0.96) | 0.001 |
| Model 1 | 2.34 (1.40−3.89) | 2.11 (1.26−3.55) | Ref | 0.005 | 0.94 (0.90−0.98) | 0.003 |
| Model 2b | 3.19 (1.24−8.24) | 2.01 (0.72−5.58) | Ref | 0.022 | 0.88 (0.82−0.97) | 0.006 |
| Symptomatic intracranial hemorrhage | ||||||
| No. of cases (%) | 35 (17.2) | 32 (15.8) | 26 (13.0) | |||
| Crude model | 1.39 (0.81−2.42) | 1.26 (0.72−2.03) | Ref | 0.487 | 0.99 (0.95−1.02) | 0.982 |
| Model 1 | 1.31 (0.75−2.29) | 1.22 (0.70−2.15) | Ref | 0.633 | 1.00 (0.96−1.06) | 0.801 |
| Model 2c§ | 1.30 (0.66−2.18) | 1.19 (0.65−2.17) | Ref | 0.797 | 1.02 (0.96−1.07) | 0.571 |
Notes: aMultivariable regression model adjusted for demographic characteristics, and variables with P<0.1 in the univariate analysis of primary outcome including atrial fibrillation, systolic blood pressure, baseline NIHSS score, baseline ASPECT score, onset to treatment time, stroke etiology, collateral status, passes of stent retriever, vascular occlusion site, prior IVT, sICH, recanalization, blood glucose, and Hs-CRP levels. bMultivariable regression model adjusted for demographic characteristics, and variables with P<0.1 in the univariate analysis of mortality including atrial fibrillation, systolic blood pressure, baseline NIHSS score, baseline ASPECT score, stroke etiology, collateral status, passes of stent retriever, vascular occlusion site, prior IVT, sICH, recanalization, low-density lipoprotein, blood glucose, and Hs-CRP levels.
cultivariable regression model adjusted for demographic characteristics, and variables with P<0.1 in the univariate analysis of sICH including baseline NIHSS score, baseline ASPECT score, onset to treatment time, stroke etiology, collateral status, passes of stent retriever, recanalization, and blood glucose.
Abbreviations: ASPECTS, the Alberta Stroke Program Early Computed Tomography Score; Hs-CRP, hypersensitive C-reactive protein; IVT, intravenous thrombolysis; NIHSS, National Institutes of Health Stroke Scale; sICH, symptomatic intracranial hemorrhage.