Table 3.
Various Parameters According to ApaI Genotypes
| AA (n = 23) | Aa + aa (n = 483) | P value | |||||
|---|---|---|---|---|---|---|---|
| Age (years) | 65.1 | ± | 10.3 | 62.5 | ± | 10.6 | 0.244 |
| Height (cm) | 161.2 | ± | 8.5 | 162.2 | ± | 9.2 | 0.606 |
| Body weight (kg) | 62.8 | ± | 7.8 | 66.3 | ± | 11.5 | 0.149 |
| Body mass index (kg/m2) | 24.1 | ± | 2.4 | 25.1 | ± | 3.5 | 0.180 |
| FPG (mg/dL) | 163.6 | ± | 39.9 | 144.2 | ± | 55.9 | 0.102 |
| PP2 (mg/dL) | 214.8 | ± | 43.2 | 207.7 | ± | 78.5 | 0.505 |
| HbA1c (%) | 8.1 | ± | 2.1 | 7.5 | ± | 1.3 | 0.202 |
| C-peptide (ng/mL) | 3.1 | ± | 4.0 | 2.6 | ± | 1.9 | 0.589 |
| Insulin (µIU/mL) | 30.9 | ± | 80.6 | 12.2 | ± | 9.8 | 0.302 |
| HOMA-IR | 12.5 | ± | 34.7 | 4.4 | ± | 4.3 | 0.301 |
| Total cholesterol (mg/dL) | 170.0 | ± | 32.0 | 170.3 | ± | 33.8 | 0.965 |
| Triglycerides (mg/dL) | 154.1 | ± | 61.6 | 158.7 | ± | 102.4 | 0.832 |
| HDL-cholesterol (mg/dL) | 43.1 | ± | 11.2 | 45.6 | ± | 11.9 | 0.322 |
| LDL-cholesterol (mg/dL) | 100.3 | ± | 22.3 | 96.3 | ± | 28.6 | 0.511 |
| AST (IU/L) | 24.7 | ± | 7.4 | 27.9 | ± | 14.5 | 0.309 |
| ALT (IU/L) | 29.2 | ± | 13.6 | 31.0 | ± | 23.2 | 0.703 |
Notes: Data are expressed as mean ± standard deviation (SD). P values were calculated using Student’s t-test.
Abbreviations: FPG, fasting plasma glucose; PP2, post-prandial 2 h glucose; HbA1c, hemoglobin A1c; HOMA-IR, homeostatic model assessment for insulin resistance; HDL, high-density lipoprotein; LDL, low-density lipoprotein; AST, aspartate aminotransferase; ALT, alanine aminotransferase.