TABLE 3.
Name | FC | P-value | VIP | ESI−/+ |
D-(-)-quinic acid | 462.2 | 3.17E-05 | 4.7 | + |
Gluconic acid | 366.0 | 3.13E-05 | 3.7 | − |
Indole-5-carboxylic acid (98%) | 142.5 | 1.98E-04 | 3.1 | − |
D-galactonic acid | 119.8 | 1.82E-05 | 3.7 | + |
Pyrophosphate | 111.1 | 8.50E-06 | 3.0 | − |
(R)-lipoic acid | 60.5 | 1.82E-04 | 3.2 | + |
Mesaconic acid | 51.6 | 7.52E-04 | 2.5 | − |
2-methylsuccinic acid | 40.5 | 1.75E-03 | 2.9 | + |
Indole-3-lactic acid | 39.0 | 2.08E-05 | 2.3 | − |
2-hydroxy-2-methylbutanedioic acid | 34.9 | 2.09E-03 | 2.2 | − |
6-phosphogluconic acid | 32.6 | 8.44E-04 | 2.7 | + |
2-(2-hydroxy-3-methylbutanamido)-4-methylpentanoic acid | 27.2 | 8.80E-05 | 2.5 | + |
Kojic acid | 16.5 | 1.71E-03 | 2.2 | + |
Kinic acid | 15.5 | 6.28E-04 | 1.7 | − |
Suberic acid | 12.1 | 1.77E-03 | 1.6 | − |
2-(acetylamino)-4-(methylthio) butanoic acid | 9.7 | 7.48E-04 | 1.4 | − |
Uric acid | 9.1 | 8.48E-05 | 1.7 | + |
Elaidic acid | 7.6 | 5.72E-03 | 1.3 | − |
2-ketoadipic acid | 7.0 | 2.65E-02 | 1.3 | − |
4-oxododecanedioic acid | 6.3 | 5.18E-04 | 1.4 | + |
D-α-Hydroxyglutaric acid | 5.9 | 1.09E-02 | 1.1 | − |
3-[(methoxycarbonyl) amino]-2,2,3-trimethylbutanoic acid | 5.3 | 3.82E-03 | 1.1 | − |
4-(2,3-dihydro-1,4-benzodioxin-6-yl) butanoic acid | 4.1 | 5.49E-04 | 1.1 | + |
FC, fold change; P-value from univariate analysis (t-test); VIP, variable importance in the projection (VIP) value of the first principal component of PLS-DA model.