Table 7.
Univariate correlation analyses of chemoresponse in gestational trophoblastic neoplasia patients with FIGO stage IV and its special type
| Variables/categories | Chemoreponse (no. of patients) | P value | ||
|---|---|---|---|---|
| Sensitive | Resistant | Dependent | ||
| Age (years) | 0.146 | |||
| < 40 | 12 | 2 | 3 | |
| ≥ 40 | 3 | 4 | 2 | |
| Blood type | 0.340 | |||
| A/+ | 4 | 3 | 3 | |
| B/+ | 5 | 2 | 1 | |
| AB/+ | 4 | 0 | 0 | |
| O/+ | 0 | 1 | 1 | |
| Antecedent pregnancy | 1.000 | |||
| Molar | 3 | 2 | 1 | |
| Term | 5 | 2 | 2 | |
| Abortion | 5 | 2 | 2 | |
| Ectopic | 2 | 0 | 0 | |
| Interval (months) | 0.940 | |||
| ≤ 6 | 5 | 3 | 1 | |
| 7–12 | 3 | 1 | 1 | |
| > 12 | 7 | 2 | 3 | |
| LogHCG level (IU/L) | 0.707 | |||
| ≤ 5 | 11 | 5 | 3 | |
| > 5 | 4 | 1 | 2 | |
| Maximum diameter (cm) | 0.563 | |||
| < 5 | 9 | 2 | 3 | |
| ≥ 5 | 6 | 4 | 2 | |
| Number of tumor lesions | 0.007 | |||
| ≤ 8 | 11 | 0 | 3 | |
| > 8 | 4 | 6 | 2 | |
| Metastatic sites | 0.792 | |||
| Lung or reproductive organs and other organs | 11 | 5 | 5 | |
| Only special sites | 4 | 1 | 0 | |
| FIGO score | 0.242 | |||
| ≤ 12 | 5 | 1 | 0 | |
| ≥ 13 | 2 | 3 | 1 | |
| Primary chemotherapy regimen is EMA-CO or EP-EMA | 0.002 | |||
| Yes | 14 | 1 | 3 | |
| No | 1 | 5 | 2 | |
| Surgery | 0.167 | |||
| Yes | 9 | 6 | 4 | |
| No | 6 | 0 | 1 | |
| Pathological pattern | 0.994 | |||
| Choriocarcinoma | 4 | 3 | 2 | |
| ETT | 2 | 1 | 1 | |
| PSTT | 1 | 1 | 0 | |
| Invasive mole | 2 | 1 | 0 | |
| Coexisting | 1 | 0 | 1 | |