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. 2021 Jan 22;141(3):455–466. doi: 10.1007/s00401-020-02260-5

Table 1.

Patient characteristics, survival data, and treatment information

No. Gender Location WHO grade Age at operation (years) EFS (years) Event OS (years) Outcome Subgroup Postoperative treatment
1 M 3rd ventricle III 12.80 7.43 Second tumor 7.62 Dead RELA-like HIT-2000
2 F Hemispheric III 4.24 11.68 Censored 11.68 Alive RELA-like HIT-2000
3 F Hemispheric III 1.90 7.68 Censored 7.68 Alive RELA-like HIT-2000
4 F Pineal region III 7.18 8.53 Censored 8.53 Alive RELA-like HIT-2000
5 M Hemispheric III 17.30 7.23 Censored 7.23 Alive RELA-like HIT-2000/E-HIT 2004
6 M Lateral ventricle III 0.52 4.90 Relapse 5.60 Dead RELA-like VEC-Chemotherapy; UKCCSG/SIOP
7 F Lateral ventricle III 4.20 5.49 Censored 5.49 Alive RELA-like HIT-2000
8 M Hemispheric III 6.55 7.48 Censored 7.48 Alive RELA-like HIT-2000
9 M Hemispheric III 2.32 n.a. n.a. n.a. n.a. RELA-like n.a.
10 M 3rd ventricle II 15.00 10.40 Censored 10.40 Alive Tanycytic HIT-2000
11 F Hemispheric III 13.64 5.58 Censored 5.58 Alive Tanycytic I-HIT-MED
12 M Hemispheric II 14.90 3.38 Censored 3.38 Alive Tanycytic I-HIT-MED
13 F Hemispheric II 6.90 n.a. n.a. n.a. n.a. Tanycytic n.a.
14 M Hemispheric II 17.80 2.80 Censored 2.80 Alive Tanycytic Irradiation only
15a F Pineal region II 10.30 6.90 Censored 6.90 Alive Tanycytic Irradiation only
16 F Hemispheric III 13.50 6.78 Censored 6.78 Alive Astroblastoma-like HIT-2000
17 F Hemispheric III 5.25 8.61 Censored 8.61 Alive Astroblastoma-like HIT-2000
18b M 3rd ventricle III 9.38 1.70 Censored 1.70 Alive Other I-HIT-MED

NF2 neurofibromatosis type 2; VEC vincristine, etoposide, cyclophosphamide; PFB posterior fossa ependymoma, group B

aNF2 patient

bGenetically classified as PFB ependymoma