Table 4.

Performance of different methods tested with leave-one-out cross-validation.

Method	Sn (%)	Sp (%)	Acc (%)	Str (%)	Matthews correlation coefficient
IGPCR-Drug	78.3	91.4	86.9	84.9	0.71
OET-KNN	77.8	88.7	85.0	83.3	0.67
QuickRBF	74.8	92.4	86.4	83.6	0.69
SVM	74.2	92.7	86.4	83.6	0.69
RF	76.5	92.9	87.3	84.7	0.71
RF + PPP	79.7	92.8	88.3	86.3	0.73
DWKNN	81.4	84.7	83.6	83.1	0.64
DWKNN(Ensemble)	81.1	87.1	85.1	84.1	0.67
BOW-GBDT	79.5	93.1	88.5	86.3	0.74

Italic mean that they are the best scores compared with other methods.