Table 3.
AUC statistics per protein and combined proteins, for the classification status of DVD group from other groups.
| Variable protein name/gene name | Optimal cutpoint | Sensitivity | 1-Specificity | Euclidean's index | AUC | CI. low | CI. high | P-value |
|---|---|---|---|---|---|---|---|---|
| P00738 | 885,561,904 | 0.917 | 0.386 | 0.155885 | 0.785 | 0.656 | 0.915 | 0.002 |
| P05546 | 1268692,696 | 0.583 | 0.088 | 0.181633 | 0.725 | 0.537 | 0.913 | 0.015 |
| P24539 | 1,251,574,887 | 0.667 | 0.211 | 0.15541 | 0.730 | 0.561 | 0.898 | 0.013 |
| O95498 | 389491398.9 | 1 | 0.263 | 0.069169 | 0.829 | 0.731 | 0.927 | 0.000 |
| Q6PKA6 | 452319949.4 | 0.583 | 0.246 | 0.234405 | 0.731 | 0.582 | 0.880 | 0.012 |
| A0A5C2GRG5 | 170,596,212 | 0.833 | 0.263 | 0.097058 | 0.848 | 0.750 | 0.946 | 0.000 |
| A0A5C2FZ29 | 186896857.4 | 0.667 | 0.158 | 0.135853 | 0.737 | 0.537 | 0.937 | 0.010 |
| B5BU25 | 28141947.62 | 0.667 | 0.193 | 0.148138 | 0.703 | 0.498 | 0.908 | 0.028 |
| P13671 | 74615703.49 | 0.667 | 0.263 | 0.180058 | 0.773 | 0.620 | 0.927 | 0.003 |
| P00738+P05546 | 0.1391723 | 0.75 | 0.175 | 0.093125 | 0.779 | 0.599 | 0.959 | 0.002 |
| P00738+P24539 | 0.1041441 | 0.917 | 0.298 | 0.095693 | 0.858 | 0.748 | 0.968 | 0.000 |
| P00738+O95498 | 0.1008949 | 0.917 | 0.316 | 0.106745 | 0.857 | 0.758 | 0.955 | 0.000 |
| P00738+Q6PKA6 | 0.1210192 | 0.75 | 0.211 | 0.107021 | 0.842 | 0.736 | 0.948 | 0.000 |
| P00738+A0A5C2GRG5 | 0.1729689 | 0.667 | 0.123 | 0.126018 | 0.833 | 0.716 | 0.951 | 0.000 |
| P00738+A0A5C2FZ29 | 0.2170247 | 0.667 | 0.14 | 0.130489 | 0.765 | 0.586 | 0.943 | 0.004 |
| P00738+B5BU25 | 0.1094936 | 0.833 | 0.193 | 0.065138 | 0.886 | 0.795 | 0.977 | 0.000 |
| P00738+P13671 | 0.1254628 | 0.75 | 0.281 | 0.141461 | 0.781 | 0.623 | 0.938 | 0.002 |
| P05546+P24539 | 0.1269705 | 0.75 | 0.316 | 0.162356 | 0.773 | 0.623 | 0.924 | 0.003 |
| P05546+O95498 | 0.248127 | 0.583 | 0.088 | 0.181633 | 0.781 | 0.632 | 0.930 | 0.002 |
| P05546+Q6PKA6 | 0.1240923 | 0.75 | 0.263 | 0.131669 | 0.794 | 0.644 | 0.943 | 0.001 |
| P05546+A0A5C2GRG5 | 0.1329428 | 0.667 | 0.211 | 0.15541 | 0.768 | 0.605 | 0.930 | 0.004 |
| P05546+A0A5C2FZ29 | 0.1077113 | 0.833 | 0.211 | 0.07241 | 0.819 | 0.638 | 1.000 | 0.001 |
| P05546+B5BU25 | 0.3128123 | 0.833 | 0.053 | 0.030698 | 0.925 | 0.838 | 1.000 | 0.000 |
| P05546+P13671 | 0.1352016 | 0.75 | 0.263 | 0.131669 | 0.791 | 0.630 | 0.952 | 0.002 |
| P24539+O95498 | 0.1303219 | 0.917 | 0.281 | 0.08585 | 0.819 | 0.695 | 0.943 | 0.001 |
| P24539+Q6PKA6 | 0.1686308 | 0.667 | 0.246 | 0.171405 | 0.740 | 0.566 | 0.913 | 0.009 |
| P24539+A0A5C2GRG5 | 0.1009088 | 0.917 | 0.316 | 0.106745 | 0.842 | 0.729 | 0.955 | 0.000 |
| P24539+A0A5C2FZ29 | 0.1652986 | 0.75 | 0.193 | 0.099749 | 0.887 | 0.790 | 0.985 | 0.000 |
| P24539+B5BU25 | 0.1958116 | 0.833 | 0.14 | 0.047489 | 0.887 | 0.792 | 0.983 | 0.000 |
| P24539+P13671 | 0.1278419 | 0.667 | 0.333 | 0.221778 | 0.792 | 0.657 | 0.927 | 0.002 |
| O95498+Q6PKA6 | 0.1110988 | 0.917 | 0.316 | 0.106745 | 0.836 | 0.735 | 0.937 | 0.000 |
| O95498+A0A5C2GRG5 | 0.0934431 | 0.833 | 0.316 | 0.127745 | 0.846 | 0.744 | 0.949 | 0.000 |
| O95498+A0A5C2FZ29 | 0.1131648 | 0.75 | 0.211 | 0.107021 | 0.825 | 0.686 | 0.963 | 0.000 |
| O95498+B5BU25 | 0.102268 | 0.917 | 0.281 | 0.08585 | 0.883 | 0.792 | 0.974 | 0.000 |
| O95498+P13671 | 0.1913238 | 0.667 | 0.158 | 0.135853 | 0.836 | 0.708 | 0.965 | 0.000 |
| Q6PKA6+A0A5C2GRG5 | 0.1053598 | 0.833 | 0.228 | 0.079873 | 0.874 | 0.780 | 0.969 | 0.000 |
| Q6PKA6+A0A5C2FZ29 | 0.1107437 | 0.75 | 0.211 | 0.107021 | 0.873 | 0.762 | 0.984 | 0.000 |
| Q6PKA6+B5BU25 | 0.1230676 | 0.833 | 0.14 | 0.047489 | 0.864 | 0.742 | 0.986 | 0.000 |
| Q6PKA6+P13671 | 0.1606209 | 0.667 | 0.211 | 0.15541 | 0.851 | 0.735 | 0.967 | 0.000 |
| A0A5C2GRG5+A0A5C2FZ29 | 0.1775901 | 0.75 | 0.123 | 0.077629 | 0.825 | 0.676 | 0.973 | 0.000 |
| A0A5C2GRG5+B5BU25 | 0.140421 | 0.833 | 0.14 | 0.047489 | 0.924 | 0.858 | 0.990 | 0.000 |
| A0A5C2GRG5+P13671 | 0.2018078 | 0.667 | 0.105 | 0.121914 | 0.816 | 0.673 | 0.959 | 0.001 |
| A0A5C2FZ29+B5BU25 | 0.1353738 | 0.75 | 0.175 | 0.093125 | 0.882 | 0.795 | 0.968 | 0.000 |
| A0A5C2FZ29+P13671 | 0.2593937 | 0.667 | 0.088 | 0.118633 | 0.788 | 0.606 | 0.970 | 0.002 |
| B5BU25+P13671 | 0.1484973 | 0.75 | 0.105 | 0.073525 | 0.898 | 0.810 | 0.985 | 0.000 |
AUC, area under the curve; CI, 95% confidence interval. Bold represents the top 5 AUC.