Table 3.
Latent Class Contrasts
| Contrast | |||
|---|---|---|---|
| Persistent Rx Misuse vs. Desistant Cannabis Use | Persistent Polydrug Use vs. Desistant Party Drug Use | Persistent Polydrug Use vs. Persistent Rx Misuse | |
| Reference Category | Desistant Cannabis Use | Desistant Party Drug Use | Persistent Rx Misuse |
| Demographics | Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) |
| Sex | 0.14 (0.09–0.20) | 2.07 (1.45–2.97) | 6.28 (3.61–10.91) |
| Marital status | 0.98 (0.68–1.43) | 3.48 (2.20–5.50) | 7.80 (4.34–14.04) |
| Education | 0.98 (0.86–1.11) | 0.86 (0.76–0.97)* | 0.86 (0.72–1.02) |
| Lifetime Drugs Used | Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) |
| 5.06 (3.84–6.66) | 7.34 (5.44–9.90) | 14.30 (6.95–29.43) | |
| Age of First Use | Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) |
| Alcohol | 1.01 (0.91–1.13) | 0.86 (0.78–0.95)** | 0.82 (0.71–0.95)* |
| Nicotine | 0.99 (0.93–1.05) | 0.97 (0.87–1.03) | 0.99 (0.91–1.06) |
| Cannabis | 0.99 (0.93–1.06) | 0.88 (0.82–0.96)** | 0.83 (0.75–0.92)** |
| Opportunity to Use | Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) |
| Cannabis | 0.04 (0.01–0.16) | - | - |
| Stimulants | 0.58 (0.36–0.94)* | 2.46 (0.51–11.93) | 16.28 (1.58–168.02)* |
| Cocaine/Crack | 0.66 (0.37–1.17) | 2.54 (1.26–5.14)* | 66.06 (13.54–322.19) |
| Hallucinogens | 0.34 (0.19–0.60)*** | 2.34 (1.17–4.67)* | 34.51 (8.26–144.27) |
| Opioids | 39.61 (23.29–67.39) | 3.08 (1.86–5.10) | 0.24 (0.06–0.98)* |
| Sedatives | 3.35 (1.86–6.01) | 4.26 (2.64–6.88) | 10.66 (2.59–43.84)** |
| Inhalants | 0.55 (0.28–1.07) | 4.29 (2.65–6.95) | 22.48 (6.13–82.45) |
| Dissociatives | 0.29 (0.06–1.57) | 5.53 (3.43–8.89) | - |
| Solvents | 0.47 (0.20–1.12) | 1.54 (0.85–2.77) | 1.69 (0.37–7.61) |
| Perceived Peer Drug Use | Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) |
| Male Friends | 0.37 (0.19–0.72)** | 7.15 (2.84–18.01) | 9.20 (6.98–57.31) |
| Female Friends | 1.45 (0.69–3.03) | 3.94 (2.30–6.75) | 4.66 (1.82–11.96)*** |
| Coworkers | 1.97 (0.64–6.03) | 2.78 (1.37–5.58)** | 6.68 (1.50–28.83)* |
| Lifetime Use Disorder | Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) |
| Alcohol | 0.68 (0.49–0.95)* | 1.15 (0.73–1.81) | 1.73 (0.89–3.38) |
| Nicotine | 1.16 (0.83–1.64) | 1.04 (0.69–1.57) | 1.21 (0.63–2.31) |
| Cannabis | 1.04 (0.65–1.66) | 1.62 (1.05–2.48)* | 6.14 (23.13–12.07) |
| Stimulants | - | 3.95 (2.64–5.89) | 28.01 (11.82–66.37) |
| Cocaine/Crack | - | 2.78 (1.37–5.61)** | - |
| Hallucinogens | - | 2.51 (1.37–4.60)** | - |
| Opioids | - | 2.55 (1.22–5.31)* | 2.96 (0.71–12.32) |
| Sedatives | - | 3.18 (1.27–7.97)* | 1.06 (0.22–5.23 ) |
| Psychiatric Symptoms | Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) |
| ADHD | 0.80 (0.38–1.70) | 1.00 (0.53–1.89) | 1.06 (0.46–2.44) |
| Conduct Disorder | 1.08 (0.60–1.92) | 1.50 (0.95–2.37) | 2.40 (1.25–4.62)** |
| ASPD | 1.85 (0.77–4.47) | 3.27 (1.76–6.10)*** | 1.75 (0.74–4.12) |
| Depressive Episode | 2.38 (1.62–3.48) | 0.99 (0.66–1.49) | 0.53 (0.32–0.87)* |
| Suicidal Ideation | 1.30 (0.87–1.94) | 1.98 (1.34–2.91)** | 1.60 (0.96–2.66) |
| Suicide Attempt | 2.31 (1.13–4.75)* | 0.78 (0.42–1.45) | 0.80 (0.37–1.74) |
Note. Predictor reference categories: sex=female, marital status=married, opportunity to use=no, use disorder=not present; psychiatric symptoms=not present; ADHD=attention deficit/hyperactivity disorder; ASPD=antisocial personality disorder; dash (–) indicates at least one cell N being too low to accurately estimate contrast (N=0–5); Bonferroni-corrected p=.0002; bold indicates significance, p≤.0001 unless noted;
***
p≤.0005,
**
p≤.005,
*
p<.05.