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. 2021 Feb 15;11:3. doi: 10.1186/s12348-020-00234-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Decreased levels of IgE and paradoxical transient eosinophilia in peripheral blood after dupilumab therapy. IgE level decreased markedly from 23,100 IU/mL at 3 weeks before to 8520 IU/mL at 10 weeks after dupilumab administration (a). The number of eosinophils paradoxically increased from 365 cells/μL at 3 weeks before to 1400 cells/μL at 10 weeks after dupilumab administration (b)