Table 2.

Univariate and multivariate analyses of progression-free survival.

Parameter	Univariate analysis			Multivariate analysis
	HR	95% CI	P	HR	95% CI	P
Sex  Male vs Female	0.769	0.509–1.162	0.213
Age  ≥ 60 vs <60	0.825	0.540–1.260	0.373
Tumor differentiation  Moderate vs. poorly	0.629	0.375–1.056	0.080	0.444	0.25–0.777	0.004
LAUREN  Diffuse vs intestinal	0.928	0.522–1.649	0.799	2.009	1.257–3.210	0.004
Tumor location  Body vs antrum	1.614	1.034–2.519	0.035
PD-L1 status  Negative vs Positive	0.547	0.339–0.883	0.014	0.596	0.364–0.975	0.039
HER-2 status  Negative vs Positive	0.416	0.240–0.722	0.002	0.280	0.149–0.525	0.000