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. 2021 Feb 1;10:608836. doi: 10.3389/fonc.2020.608836

Table 3.

Univariate and multivariable analysis of factors associated with overall survival of MAC of RCC.

Variable Univariate Multivariable
RR(95%CI) P RR(95%CI) P
Race
White 1 0.215
Black 0.970(0.809–1.164)
Others 0.800(0.623–1.028)
Age (years)
≤60 1 <0.001 1 <0.001
>60 1.672(1.443–1.938) 1.783(1.525–2.084)
Sex
Female 1 0.707
Male 0.979(0.876–1.094)
CEA
Normal 1 <0.001 1 <0.001
Elevated 1.927(1.722–2.157) 1.467(1.300–1.656)
PNI
Absent 1 <0.001 0.001
Present 2.034(1.734–2.386) 1.312(1.110–1.551)
Size (cm)
≤5 1 0.003 1 0.863
>5 1.183(1.058–1.324) 1.010(0.897–1.138)
Tumor number
Solitary 1 <0.001 1 <0.001
Multiple 1.237(1.101–1.388) 1.246(1.107–1.403)
Location
Cecum 1 0.779
Ascending 1.012(0.892–1.148)
Hepatic Flexure 0.903(0.726–1.123)
Transverse Colon 1.014(0.862–1.193)
Differentiation
Grade I/Grade II 1 <0.001 1 0.011
Grade III/Grade IV 1.492(1.323–1.683) 1.175(1.038–1.330)
Stage(TNM 7ed)
I 1 <0.001 1 <0.001
II 1.127(0.890–1.428) 1.091(0.855–1.392)
III 1.981(1.573–2.495) 2.872(2.241–3.681)
IV 6.599(5.214–8.352) 9.854(7.526–12.902)
Surgery type
PC 1 0.599
RHC 1.039(0.902–1.197)
Postoperative chemotherapy
No/Unknown 1 0.073 1 <0.001
Yes 1.108(0.990–1.240) 0.480(0.419–0.551)