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. 2021 Feb 1;10:608836. doi: 10.3389/fonc.2020.608836

Table 4.

Univariate and multivariable analysis of factors associated with cancer-specific survival of MAC of RCC.

Variable Univariate Multivariate
RR(95%CI) P RR(95%CI) P
Race
White 1 0.201
Black 1.154(0.935–1.425)
Others 0.846(0.624–1.148)
Age (years)
≤ 60 1 0.010 1 <0.001
>60 1.244(1.053–1.470) 1.603(1.342–1.916)
Sex
Female 1 0.415
Male 0.944(0.823–1.084)
CEA
Normal 1 <0.001 1 <0.001
Elevated 2.291(1.986–2.643) 1.428(1.225–1.664)
PNI
Absent 1 <0.001 1 <0.001
Present 2.864(2.404–3.412) 1.436(1.196–1.726)
Size (cm)
≤5 1 <0.001 1 0.076
>5 1.428(1.239–1.645) 1.143(0.986–1.326)
Tumor number
Solitary 1 0.454
Multiple 0.944(0.812–1.098)
Location
Cecum 1 0.269
Ascending 0.875(0.747–1.025)
Hepatic Flexure 0.844(0.644–1.107)
Transverse Colon 0.999(0.820–1.217)
Differentiation
Grade I/Grade II 1 <0.001 1 0.001
Grade III/Grade IV 1.870(1.620–2.158) 1.288(1.112–1.493)
Stage(TNM 7ed)
I 1 <0.001 1 <0.001
II 2.239(1.331–3.765) 2.002(1.183–3.385)
III 7.720(4.674–12.751) 9.293(5.553–15.554)
IV 31.162(18.860–51.489) 36.099(21.298–61.187)
Surgery type
PC 1 0.407
RHC 1.078(0.903–1.287)
Postoperative chemotherapy
No/Unknown 1 <0.001 1 <0.001
Yes 0.534(0.466–0.612) 0.571(0.488–0.669)