Table 3.
Comparison Phenotypic and Genotypic DST Results of MTBC Isolates
| Drug Susceptibility Test | Type of Drugs | No. of Isolates | MGIT SIRE DST | Sensitivity (95% Cl) |
Specificity (95% Cl) |
PPV (95% Cl) |
NPV (95% Cl) |
AUC (95% Cl) |
|
|---|---|---|---|---|---|---|---|---|---|
| Susceptible | Resistance | ||||||||
|
LPA MDRTBplus DST |
Susceptible | 63 | 1 | 94.4% (72.7–99.7) | 100% (94.3–100) | 100% | 98.44% (90.36–99.76) | 0.97 (0.909–0.99) | |
| Resistance | 0 | 17 | |||||||
| Susceptible | 77 | 1 | 75% (19.4–99.4) |
100% (95.32–100) |
100% | 98.72% (93.38–99.76) |
0.88 (0.783–0.94) |
||
| Resistance | 0 | 3 | |||||||
| RIF and INH | Susceptible | 79 | 0 | 100% (15.81–100) | 98.8% (93.23–100.0) | 66.7% (22.2–93.4) | 100% | 0.99 (0.99–1.00) |
|
| Resistance | 1 | 2 | |||||||
Abbreviations: INH, isoniazid; RIF, rifampicin; Cl, confidence interval; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the curve.