Figure 3.
LPS-induced expression of CAMP in 3T3-L1 adipocytes is abrogated by the NF-κB-Inhibitor BAY-11 and by the STAT3-inhibitor S3I-201 but not by the selective MAPK-inhibitor SB239063 or by the MEK-1/-2 inhibitor U0126. BAY-11 (irreversible inhibitor of IKKα and phosphorylation inhibitor of IκBα); SB239063 (selective MAPK-inhibitor); S3I-201 (STAT3-inhibitor; signal transducer and activator of transcription-3); U0126 (inhibitor of Raf-activated MEK-1/-2). The overnight incubation time was 18 h. The Kruskal–Wallis test was applied for calculating statistical significance. Ctrl.: control.
