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. 2021 Jan 31;21(4):241. doi: 10.3892/ol.2021.12502

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Copyright: © Tang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Stratified comparisons of IL10 CpG island methylation between tumor tissues and paired para-tumor tissues. P-values were calculated using Wilcoxon rank sum test. Stratified tests were performed according to tumor differentiation, Borrmann type, smoking history and family history of cancer. Plots are presented as median with interquartile range. A significant P-value was identified in the following subgroups: Low differentiation, III+IV Borrmann types, non-smoker patients and patients with no family history of cancer. IL10, interleukin 10; N, normal adjacent tissue; PMR, percentage of methylated reference; T, tumor tissue.