Table II.
Association between SQLE expression and clinicopathological parameters of patients with ductal carcinoma in situ (n=79).
| Characteristics | High SQLE expression, n/total n (%) | P-valuea |
|---|---|---|
| Age, years | >0.05 | |
| ≤50 | 21/45 (46.7) | |
| >50 | 17/34 (50.0) | |
| Size, cm | >0.05 | |
| ≤2.5 | 21/45 (46.7) | |
| >2.5 | 17/34 (50.0) | |
| Nuclear grade | <0.01 | |
| 1 | 1/7 (14.3) | |
| 2 | 19/46 (41.3) | |
| 3 | 18/26 (69.2) | |
| Comedo-type necrosis | <0.05 | |
| No | 11/32 (34.4) | |
| Yes | 27/47 (57.4) | |
| Estrogen receptor-α | >0.05 | |
| Negative | 17/28 (60.7) | |
| Positive | 21/51 (41.2) | |
| HER2 | <0.01 | |
| Negative | 18/51 (35.3) | |
| Positive | 20/28 (71.4) | |
| Recurrence | >0.05b | |
| No | 33/72 (45.8) | |
| Yes | 5/7 (71.4) |
a
Analyzed by χ2 test
b
Analyzed by Fishers exact test. SQLE, squalene epoxidase.